Fig. 1

Study design of a survey of gut microbiota in canine immune-mediated hematological disease. A Fecal samples of healthy dogs were collected once both from the disease in-contact and non-in-contact dogs. Samples of diseased dogs were collected at presentation (week 0/baseline) and week 2 and week 8 after treatment. B Assessments of the clinical response of IMHA (PCV %) or ITP (platelet count × 1000/μL) patients at weeks 0, 2, and 8. The normal values of PCV and platelet counts are depicted by shading. IMHA: immune-mediated hemolytic anemia, ITP: immune thrombocytopenia, PCV: packed cell volume