Fig. 7

A Classification of measured metabolites according to chemical class in serum using 1H-NMR. B partial least square discriminant analysis (PLS-DA) score plot of serum. C abundance of lipids and D amino acids. E metabolic pathway mapping of common quantified metabolites in the serum. F abundance of serum metabolites and liver enzymes using UV spectroscopy and colorimetry method. Selected metabolites obtained from 1H-NMR met the criteria of P < 0.1 and VIP score ≥ 1.5. CON, without PEO; PEO, Pinus koraiensis cone essential oil; ALT/SGPT, alanine transaminase/serum glutamic pyruvate transaminase; AST/SGOT, aspartate aminotransferase/serum glutamic oxaloacetic transaminase; BUN: blood urea nitrogen. *P < 0.1, **P < 0.05