Skip to main content

Table 2 Antimicrobial resistance genes (ARGs) that significantly changed over time by treatment group

From: Effects of dietary zinc on the gut microbiome and resistome of the gestating cow and neonatal calf

 

Zinc Supplemented

Control

ARG

Estimate1

Adjusted

p-value2

Estimate

Adjusted

p-value

arlR

7.1509

0.2255

10.9530

0.0214

arlS

2.9502

0.0355

2.6930

0.0646

cdeA

3.5636

0.0304

2.4459

0.2217

cfrE

0.8622

0.0308

0.2034

0.9101

dfrA3

2.1163

0.0444

0.6668

0.8339

lmrB

2.3599

0.0010

2.7245

0.0001

lmrS

2.1961

0.0039

2.4724

0.0009

lnuC

-18.7741

0.0601

-23.1099

0.0126

lsaC

1.4686

0.0126

0.7231

0.4155

lsaE

2.7616

0.0458

0.8865

0.8282

macB

8.5596

0.0103

4.8985

0.2642

mel

-9.4694

0.2096

-18.2777

0.0016

msrA

0.6374

0.0041

0.3842

0.1743

msrC

1.1886

0.0227

-0.0343

0.9997

pmrE

13.3181

0.0069

8.6881

0.1380

sul4

4.4135

0.0003

7.4272

1.93E-09

TaeA

12.0411

0.0002

10.0349

0.0022

tet(32)

-2.3022

0.0339

-2.0473

0.0726

tet(37)

4.2348

0.0320

0.6573

0.9723

tet(O/32/O)

-1.0878

0.0209

-0.8546

0.1012

tetA

3.4244

0.0098

1.1255

0.7141

vanP

0.8327

0.1211

1.0066

0.0405

vanRB

3.8056

0.0063

5.2552

0.0001

vanRF

7.8844

0.0380

5.3077

0.2623

vanRL

3.5750

0.0008

3.2982

0.0022

vanRO

2.0287

0.1139

3.1476

0.0040

vanRP

1.7231

0.3115

2.6523

0.0443

vanSL

0.6593

0.0278

0.7794

0.0063

vgaB

1.1528

0.1145

2.1650

0.0003

vgaC

1.0612

0.0389

1.6303

0.0004

vgaE

1.3739

0.0306

2.1188

0.0002

  1. 1Linear mixed effect models estimated change of log2 transformed RPKM values between study groups
  2. 2P-value adjusted for post-hoc multiple comparisons with Tukey’s method