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Fig. 3 | Animal Microbiome

Fig. 3

From: Multi-omics integration and immune profiling identify possible causal networks leading to uterine microbiome dysbiosis in dairy cows that develop metritis

Fig. 3

Illustration of our working hypothesis of the interactions between prepartum body weight, body weight loss, systemic immune profiling, and uterine and plasma metabolome around parturition and how they may affect uterine opportunistic pathogens growth leading to metritis development. Down arrows indicate reduction, and up arrows indicate increase in cows with metritis. ROS: reactive oxygen species. MetO: methionine sulfoxide. CHO: carbohydrates. IL: interleukin. PMN: polymorphonuclear cells. IFN: interferon. MHC: major histocompatibility complex. DMI: dry matter intake. NNB: negative nutrient balance. Mo: monocytes. Mϕ: macrophages. Figure created with Biorender

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Animal Microbiome

ISSN: 2524-4671