Fig. 5

Administering A. muciniphila to dextran sulfate sodium (DSS)-treated piglets aggravated intestinal inflammation. Values are means, with their standard errors represented by vertical bars (n = 6). Bars that do not share the same superscripts are significantly different (P < 0.05). CON, pigs were fed with a basal diet; CA, pigs were gavaged every day with 1 × 10¹¹ CFU/10 mL A. muciniphila (DSM 22959); DCON, pigs were fed with a basal diet and challenged by DSS; DA, pigs were gavaged every day with 1 × 10¹¹ CFU/10 mL A. muciniphila (DSM 22959) and challenged by DSS. IL1β interleukin-1β, IL4 interleukin-4, IL6 interleukin-6, IL10 interleukin-10, IL17A interleukin-17 A, IL17F interleukin-17 F, IL23 interleukin-23, TNFα tumor necrosis factor-α, IFNγ interferon-gamma, RORγt retinoic acid receptor-related orphan receptor gamma t, STAT3 signal transducer and activator of transcription 3