Probiotic administration aggravates dextran sulfate sodium salt-induced inflammation and intestinal epithelium disruption in weaned pig

Table 2 Effect of A. muciniphila supplementation on growth performance and diarrhea rate in weaned pigs upon DSS challenge¹

Items	Treatments²				SEM	P-value
Items	CON	CA	DCON	DA	SEM	AKK	DSS	Interaction
9–15 day
Initial weight, kg	10.19	9.71	9.87	9.4	0.62	0.29	0.48	0.99
Final weight, kg	12.98^a	12.81^ab	10.34^bc	9.37^c	0.93	0.40	< 0.01	0.55
ADFI, g/d	505.7^ab	515.3^a	364^ab	268.3^b	88.80	0.49	< 0.01	0.40
ADG, g/d	398.6^a	442.9^a	67.14^b	-4.286^b	80.96	0.82	< 0.01	0.33
F: G	-	-	-	-	-	-	-	-
Diarrhea rate, %	17.50^b	7.50^b	25.00^ab	42.50^a	8.00	0.51	< 0.01	0.02

ADFI average daily feed intake, ADG average daily gain, F: G Feed: Gain ratio
¹ Mean and total SEM are list in Separate columns, n = 6
² CON, pigs were fed with a basal diet; CA, pigs were gavaged every day with 1 × 10¹¹ CFU/10 mL A. muciniphila (DSM 22959); DCON, pigs were fed with a basal diet and challenged by DSS; DA, pigs were gavaged every day with 1 × 10¹¹ CFU/10 mL A. muciniphila (DSM 22959) and challenged by DSS
^{a, b, c} mean values within a row with unlike superscript letters were significantly different, P < 0.05

ISSN: 2524-4671