Probiotic administration aggravates dextran sulfate sodium salt-induced inflammation and intestinal epithelium disruption in weaned pig

Table 3 Effects of A. muciniphila supplementation on organ index in weaned pigs upon DSS challenge¹

Items	Treatments²				SEM	P-value
Items	CON	CA	DCON	DA	SEM	AKK	DSS	Interaction
Heart index, %	0.53	0.51	0.82	0.63	0.13	0.31	0.04	0.43
Liver index, %	2.53	2.68	2.90	2.53	0.24	0.54	0.51	0.15
Spleen index, %	0.21	0.21	0.30	0.25	0.04	0.36	0.02	0.45
Lung index, %	1.61	1.83	2.32	2.67	0.42	0.35	0.02	0.83
Kidney index, %	0.48^b	0.52^ab	0.59^a	0.58^ab	0.03	0.64	< 0.01	0.39

¹ Mean and total SEM are list in Separate columns, n = 6
² CON, pigs were fed with a basal diet; CA, pigs were gavaged every day with 1 × 10¹¹ CFU/10 mL A. muciniphila (DSM 22959); DCON, pigs were fed with a basal diet and challenged by DSS; DA, pigs were gavaged every day with 1 × 10¹¹ CFU/10 mL A. muciniphila (DSM 22959) and challenged by DSS
^{a, b} mean values within a row with unlike superscript letters were significantly different, P < 0.05

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