Fig. 4

Cytoscape networks showing the Reactome pathway analysis results. Pathway analysis of all differentially expressed genes (935) resulted in 88 overrepresented pathways that were grouped into 11 parent categories (A). The immune system overrepresented pathways are shown in detail in B. Numbers within nodes represent number of genes in each pathway or category. Edge thickness represent number of shared genes. The node color gradient in A represents the number of enriched pathways within each category. The node color in B represents different groups of pathways: Blue: Interleukin related pathways, Dark green: MHCI related pathways, Light green: interferon related pathways, Purple: colony-stimulating factor 3 signaling related pathways