Fig. 2
From: Idiopathic epilepsy in dogs is associated with dysbiotic faecal microbiota
Faecal microbiota comparison of healthy (n = 17) and epileptic (n = 19) dogs. A) Relative microbial abundance (genus level). Only taxa with a relative abundance ≥ 2% are displayed. B) Box-plot of α-diversity calculated with Chao1 and Shannon diversity indexes. Index comparison was performed using the Wilcoxon Rank Sum test. C) Two-dimensional principal coordinates analysis (PCoA) plot based on the Bray-Curtis dissimilarity matrix. Differences in β-diversity were estimated by permutational multivariate analysis of variance (PERMANOVA) after testing for sample dispersion. D) Differentially abundant amplicon sequence variants (ASVs) between healthy and epileptic dogs identified by DESeq2. ASVs with a log2 fold change > 2 or < 2 and adjusted p-values (q-values) > 0.05 were considered significantly associated with the health status, while only those with a log2 fold change > 3 or < 3 are shown in the volcano plot